Complex human adenoid tissue-based ex vivo culture systems reveal anti-inflammatory drug effects on germinal center T and B cells

Background: Human immunology research is often limited to peripheral blood. However, there are important differences between blood immune cells and their counterparts residing in secondary lymphoid organs, such as in the case of germinal center (GC) T follicular helper (Tfh) cells and GC B cells. Me...

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Bibliographic Details
Main Authors: Angelika Schmidt, Johanna E. Huber, Özen Sercan Alp, Robert Gürkov, Christoph A. Reichel, Matthias Herrmann, Oliver T. Keppler, Thomas Leeuw, Dirk Baumjohann
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300591