DNA methylation and hydroxymethylation profiles reveal possible role of highly methylated TLR signaling on Fasciola gigantica excretory/secretory products (FgESPs) modulation of buffalo dendritic cells

Abstract Background Excretory/secretory products (ESPs) released by parasites influence the development and functions of host dendritic cells (DCs). However, little is known about changes of DNA (hydroxy)methylation on DC development during Fasciola gigantica infection. The present study aimed to in...

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Bibliographic Details
Main Authors: Xue-Fang Mei, Wei Shi, Yao-Yao Zhang, Bin Zhu, Yu-Rui Wang, Lin-Jing Hou, Wen-Ping Zhao, Jian Li, Dong-Ying Wang, Hong-Lin Luo, Wei-Yi Huang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Parasites & Vectors
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13071-019-3615-4