Microneme Proteins 1 and 4 From Toxoplasma gondii Induce IL-10 Production by Macrophages Through TLR4 Endocytosis

Microneme Proteins 1 and 4 From Toxoplasma gondii Induce IL-10 Production by Macrophages Through TLR4 Endocytosis

The protozoan parasite Toxoplasma gondii modulates host cell responses to favor its success in the early stage of infections by secreting proteins from its apical organelles. Some of these proteins, including microneme proteins (MICs) 1 and 4, trigger pro-inflammatory host cell responses. The lectin...

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Bibliographic Details
Main Authors: Rafael Ricci-Azevedo, Flavia Costa Mendonça-Natividade, Ana Carolina Santana, Juliana Alcoforado Diniz, Maria Cristina Roque-Barreira
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
Toxoplasma gondii
MIC1
MIC4
TLR4 (Toll-like receptor 4)
Dynasore
endocytosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.655371/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.655371/full

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