Mechanical design principles of a mitotic spindle

An organised spindle is crucial to the fidelity of chromosome segregation, but the relationship between spindle structure and function is not well understood in any cell type. The anaphase B spindle in fission yeast has a slender morphology and must elongate against compressive forces. This ‘pushing...

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Bibliographic Details
Main Authors: Jonathan J Ward, Hélio Roque, Claude Antony, François Nédélec
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/03398