Role of High-Mobility Group Box-1 in Liver Pathogenesis

High-mobility group box 1 (HMGB1) is a highly abundant DNA-binding protein that can relocate to the cytosol or undergo extracellular release during cellular stress or death. HMGB1 has a functional versatility depending on its cellular location. While intracellular HMGB1 is important for DNA structur...

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Bibliographic Details
Main Authors: Bilon Khambu, Shengmin Yan, Nazmul Huda, Xiao-Ming Yin
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
ald
Online Access:https://www.mdpi.com/1422-0067/20/21/5314