Loss of NF2 defines a genetic subgroup of non‐FOS‐rearranged osteoblastoma

Loss of NF2 defines a genetic subgroup of non‐FOS‐rearranged osteoblastoma

Abstract Osteoblastoma is a locally aggressive tumour of bone. Until recently, its underlying genetic features were largely unknown. During the past two years, reports have demonstrated that acquired structural variations affect the transcription factor FOS in a high proportion of cases. These rearr...

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Bibliographic Details
Main Authors: Karim H Saba, Louise Cornmark, Jakob Hofvander, Linda Magnusson, Jenny Nilsson, Hilda van denBos, Diana CJ Spierings, Floris Foijer, Johan Staaf, Otte Brosjö, Vaiyapuri P Sumathi, Suk Wai Lam, Karoly Szuhai, Judith VMG Bovée, Michal Kovac, Daniel Baumhoer, Emelie Styring, Karolin H Nord
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:The Journal of Pathology: Clinical Research
Subjects:
FOS
FOSB
NF2
WNT5A
osteoblastoma
osteosarcoma
Online Access:https://doi.org/10.1002/cjp2.172

Internet

https://doi.org/10.1002/cjp2.172

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