<i>XIST</i>-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality

<i>XIST</i>-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality

Background:<b> </b>The event of X chromosome inactivation induced by <i>XIST</i>, which is physiologically observed in females, is retained in testicular germ cell tumors (TGCTs), as a result of a supernumerary X chromosome constitution. X chromosome inactivation also occurs...

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Bibliographic Details
Main Authors: João Lobo, Sandra P. Nunes, Ad J. M. Gillis, Daniela Barros-Silva, Vera Miranda-Gonçalves, Annette van den Berg, Mariana Cantante, Rita Guimarães, Rui Henrique, Carmen Jerónimo, Leendert H. J. Looijenga
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
molecular biomarkers
testicular germ cell tumors
spermatogenesis
methylation
XIST promoter
Online Access:https://www.mdpi.com/2072-6694/11/9/1385

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https://www.mdpi.com/2072-6694/11/9/1385

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