Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis
<p>Abstract</p> <p>Background</p> <p>Glucocorticoid (GC) resistance is frequently seen in acute lymphoblastic leukemia of T-cell lineage (T-ALL). In this study we investigate the potential and mechanism of using rapamycin to restore the sensitivity of GC-resistant T-ALL...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2010-11-01
|
Series: | Journal of Experimental & Clinical Cancer Research |
Online Access: | http://www.jeccr.com/content/29/1/150 |