Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis

<p>Abstract</p> <p>Background</p> <p>Glucocorticoid (GC) resistance is frequently seen in acute lymphoblastic leukemia of T-cell lineage (T-ALL). In this study we investigate the potential and mechanism of using rapamycin to restore the sensitivity of GC-resistant T-ALL...

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Bibliographic Details
Main Authors: Mu Dezhi, Li Qiang, Gao Ju, Liu Huajun, Zhou Chenyan, Gu Ling, Ma Zhigui
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/29/1/150