Establishment of a Simple and Efficient Reverse Genetics System for Canine Adenoviruses Using Bacterial Artificial Chromosomes

Establishment of a Simple and Efficient Reverse Genetics System for Canine Adenoviruses Using Bacterial Artificial Chromosomes

Canine adenoviruses (CAdVs) are divided into pathotypes CAdV1 and CAdV2, which cause infectious hepatitis and laryngotracheitis in canid animals, respectively. They can be the backbones of viral vectors that could be applied in recombinant vaccines or for gene transfer in dogs and in serologically n...

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Bibliographic Details
Main Authors: Hiromichi Matsugo, Tomoya Kobayashi-Kitamura, Haruhiko Kamiki, Hiroho Ishida, Akiko Takenaka-Uema, Shin Murakami, Taisuke Horimoto
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
canine
adenovirus
reverse genetics
vector
bacterial artificial chromosome
Online Access:https://www.mdpi.com/1999-4915/12/7/767

Internet

https://www.mdpi.com/1999-4915/12/7/767

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