Bidentatide, a Novel Plant Peptide Derived from <i>Achyranthes bidentata</i> Blume: Isolation, Characterization, and Neuroprotection through Inhibition of NR2B-Containing NMDA Receptors

Bidentatide, a Novel Plant Peptide Derived from <i>Achyranthes bidentata</i> Blume: Isolation, Characterization, and Neuroprotection through Inhibition of NR2B-Containing NMDA Receptors

Increasing attention is being focused on the use of polypeptide-based N-methyl-d-aspartate (NMDA) receptor antagonists for the treatment of nervous system disorders. In our study on <i>Achyranthes bidentata</i> Blume, we identified an NMDA receptor subtype 2B (NR2B) antagonist that exert...

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Bibliographic Details
Main Authors: Fei Ding, Yunpeng Bai, Qiong Cheng, Shu Yu, Mengchun Cheng, Yulin Wu, Xiaozhe Zhang, Xinmiao Liang, Xiaosong Gu
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
enzyme inhibitor
peptide
NMDA receptor
neuroprotection
Online Access:https://www.mdpi.com/1422-0067/22/15/7977

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https://www.mdpi.com/1422-0067/22/15/7977

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