Purification, Crystallization and Preliminary X-ray Crystallographic Studies of RAIDD Death-Domain (DD)

Purification, Crystallization and Preliminary X-ray Crystallographic Studies of RAIDD Death-Domain (DD)

Caspase-2 activation by formation of PIDDosome is critical for genotoxic stress induced apoptosis. PIDDosome is composed of three proteins, RAIDD, PIDD, and Caspase-2. RAIDD is an adaptor protein containing an N-terminal Caspase-Recruiting-Domain (CARD) and a C-terminal Death-Domain (DD). Its intera...

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Bibliographic Details
Main Authors: Hyun Ho Park, Tae-ho Jang
Format: Article
Language:English
Published: MDPI AG 2009-06-01
Series:International Journal of Molecular Sciences
Subjects:
RAIDD
PIDDosome
crystallization
Death-Domain (DD)
Online Access:http://www.mdpi.com/1422-0067/10/6/2501/

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http://www.mdpi.com/1422-0067/10/6/2501/

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