Differential Proteomic Analysis of Syncytiotrophoblast Extracellular Vesicles from Early-Onset Severe Preeclampsia, using 8-Plex iTRAQ Labeling Coupled with 2D Nano LC-MS/MS

Differential Proteomic Analysis of Syncytiotrophoblast Extracellular Vesicles from Early-Onset Severe Preeclampsia, using 8-Plex iTRAQ Labeling Coupled with 2D Nano LC-MS/MS

Aims: Previous studies have revealed that the increased shedding of syncytiotrophoblast extracellular vesicles (STBM) may lead to preeclampsia (PE). We aimed to identify the proteins carried by STBM and their potential pathological roles in early-onset severe PE. Methods: In this study, we performed...

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Bibliographic Details
Main Authors: Hongmei Li, Lei Han, Zhiling Yang, Wei Huang, Xin Zhang, Yan Gu, Yinfeng Li, Xiaojie Liu, Lijuan Zhou, Jiongyu Hu, Meijia Yu, Jing Yang, Yilin Li, Yingru Zheng, Jianxin Guo, Jian Han, Li Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Microvesicles
Microparticles
Exosomes
iTRAQ
Proteomics
Preeclampsia
Syncytiotrophoblast extracellular vesicles
Online Access:http://www.karger.com/Article/FullText/430283

Internet

http://www.karger.com/Article/FullText/430283

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