VEGFA polymorphisms and cardiovascular anomalies in 22q11 microdeletion syndrome: a case-control and family-based study

VEGFA polymorphisms and cardiovascular anomalies in 22q11 microdeletion syndrome: a case-control and family-based study

Microdeletion 22q11 in humans causes velocardiofacial and DiGeorge syndromes. Most patients share a common 3Mb deletion, but the clinical manifestations are very heterogeneous. Congenital heart disease is present in 50-80% of patients and is a significant cause of morbidity and mortality. The phenot...

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Bibliographic Details
Main Authors: JUAN FRANCISCO CALDERÓN, ALONSO R PUGA, M. LUISA GUZMÁN, CARMEN PAZ ASTETE, MARTA ARRIAZA, MARIANA ARACENA, TERESA ARAVENA, PATRICIA SANZ, GABRIELA M REPETTO
Format: Article
Language:English
Published: BMC 2009-01-01
Series:Biological Research
Subjects:
congenital heart disease
DiGeorge syndrome
genetic modifiers
VEGFA
velocardiofacial syndrome
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000400007

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000400007

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