Spinal NF-κB and chemokine ligand 5 expression during spinal glial cell activation in a neuropathic pain model.

BACKGROUND:The NF-κB pathway and chemokine (C-C motif) ligand 5 (CCL5) are involved in pain modulation; however, the precise mechanisms of their interactions in chronic neuropathic pain have yet to be established. METHODS:The present study examined the roles of spinal NF-κB and CCL5 in a neuropathic...

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Bibliographic Details
Main Authors: Qin Yin, Qin Fan, Yu Zhao, Ming-Yue Cheng, He Liu, Jing Li, Fei-Fei Lu, Jin-Tai Jia, Wei Cheng, Chang-Dong Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4312098?pdf=render