C-Peptide-based assessment of insulin secretion in the Zucker Fatty rat: a modelistic study.

A C-peptide-based assessment of β-cell function was performed here in the Zucker fatty rat, a suitable animal model of human metabolic syndrome. To this aim, a 90-min intravenous glucose tolerance test (IVGTT) was performed in seven Zucker fatty rats (ZFR), 7-to-9 week-old, and seven age-matched Zuc...

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Bibliographic Details
Main Authors: Francesco Di Nardo, Carla E Cogo, Emanuela Faelli, Micaela Morettini, Laura Burattini, Piero Ruggeri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4418729?pdf=render