Potential Roles of Muscle-Derived Extracellular Vesicles in Remodeling Cellular Microenvironment: Proposed Implications of the Exercise-Induced Myokine, Irisin

Potential Roles of Muscle-Derived Extracellular Vesicles in Remodeling Cellular Microenvironment: Proposed Implications of the Exercise-Induced Myokine, Irisin

Extracellular vesicles (EVs) have emerged as key players of intercellular communication and mediate crosstalk between tissues. Metastatic tumors release tumorigenic EVs, capable of pre-conditioning distal sites for organotropic metastasis. Growing evidence identifies muscle cell-derived EVs and myok...

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Bibliographic Details
Main Authors: Samuel Darkwah, Eun Jeong Park, Phyoe Kyawe Myint, Atsushi Ito, Michael G. Appiah, Gideon Obeng, Eiji Kawamoto, Motomu Shimaoka
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
extracellular vesicles
muscle
integrins
myokines
tumor metastasis
tissue microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.634853/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.634853/full

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