Lethality of Brucella microti in a murine model of infection depends on the wbkE gene involved in O-polysaccharide synthesis

Lethality of Brucella microti in a murine model of infection depends on the wbkE gene involved in O-polysaccharide synthesis

Brucella microti was isolated a decade ago from wildlife and soil in Europe. Compared to the classical Brucella species, it exhibits atypical virulence properties such as increased growth in human and murine macrophages and lethality in experimentally infected mice. A spontaneous rough (R) mutant st...

Full description

Bibliographic Details
Main Authors: Safia Ouahrani-Bettache, María P. Jiménez De Bagüés, Jorge De La Garza, Luca Freddi, Juan P. Bueso, Sébastien Lyonnais, Sascha Al Dahouk, Daniela De Biase, Stephan Köhler, Alessandra Occhialini
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Virulence
Subjects:
brucella
virulence
lipopolysaccharide (lps)
o-polysaccharide
glycosyltransferase
rough phenotype
atomic force microscopy
Online Access:http://dx.doi.org/10.1080/21505594.2019.1682762

Internet

http://dx.doi.org/10.1080/21505594.2019.1682762

Similar Items