Controlled Release of Neurotrophin-3 and Platelet-Derived Growth Factor from Fibrin Scaffolds Containing Neural Progenitor Cells Enhances Survival and Differentiation into Neurons in a Subacute Model of SCI

A consistent problem with stem/neural progenitor cell transplantation following spinal cord injury (SCI) is poor cell survival and uncontrolled differentiation following transplantation. The current study evaluated the feasibility of enhancing embryonic stem cell-derived neural progenitor cell (ESNP...

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Bibliographic Details
Main Authors: Philip J. Johnson, Alexander Tatara, Alicia Shiu, Shelly E. Sakiyama-Elbert
Format: Article
Language:English
Published: SAGE Publishing 2010-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368909X477273