Screening fetal losses for monosomy X with a simple PCR-based procedure

To screen for monosomy X in spontaneous fetal losses we explored a simple molecular strategy based on loss of heterozygosity at highly polymorphic X-linked loci. We developed a multiplex fluorescent procedure that allows the simultaneous amplification of five dinucleotide repeat polymorphisms in a l...

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Bibliographic Details
Main Authors: Pereira Rinaldo W., Sturzeneker Rosane, Pena Sérgio D.J.
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2000-01-01
Series:Genetics and Molecular Biology
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572000000100002