Pregabalin reduces cisplatin-induced mechanical allodynia in rats

Pregabalin reduces cisplatin-induced mechanical allodynia in rats

Although cisplatin (CDDP) is a key drug in cancer chemotherapy, CDDP-induced peripheral neuropathy is a dose-limiting factor. We previously reported that CDDP-induced peripheral neuropathy, which progressed from allodynia to hypoalgesia, was ameliorated by the administration of CDDP to rats at a spe...

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Bibliographic Details
Main Authors: Yoshihiro Seto, Miyuki Takase, Yasuhiro Tsuji, Hideto To
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Journal of Pharmacological Sciences
Subjects:
Cisplatin
Pregabalin
Allodynia
Rat
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861317300865

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http://www.sciencedirect.com/science/article/pii/S1347861317300865

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