Microvesicles derived from human Wharton’s jelly mesenchymal stem cells enhance autophagy and ameliorate acute lung injury via delivery of miR-100

Abstract Objectives Microvesicles (MVs) derived from human Wharton’s jelly mesenchymal stem cells (MSC-MVs) were demonstrated to ameliorate acute lung injury (ALI). We have previously found that MSC-MV-transferred hepatocyte growth factor was partly involved in their therapeutic effects. Since MSC-M...

Full description

Bibliographic Details
Main Authors: Wen-xia Chen, Jun Zhou, Sha-sha Zhou, Yu-dan Zhang, Tong-yu Ji, Xiao-li Zhang, Shu-min Wang, Tao Du, De-gang Ding
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-020-01617-7