Non-homologous isofunctional enzymes: A systematic analysis of alternative solutions in enzyme evolution

<p>Abstract</p> <p>Background</p> <p>Evolutionarily unrelated proteins that catalyze the same biochemical reactions are often referred to as analogous - as opposed to homologous - enzymes. The existence of numerous alternative, non-homologous enzyme isoforms presents an...

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Bibliographic Details
Main Authors: Wolf Yuri I, Galperin Michael Y, Omelchenko Marina V, Koonin Eugene V
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/5/1/31