Inclusion complexes of 2-methoxyestradiol with dimethylated and permethylated β-cyclodextrins: models for cyclodextrin–steroid interaction

Inclusion complexes of 2-methoxyestradiol with dimethylated and permethylated β-cyclodextrins: models for cyclodextrin–steroid interaction

The interaction between the potent anticancer agent 2-methoxyestradiol (2ME) and a series of cyclodextrins (CDs) was investigated in the solid state using thermal analysis and X-ray diffraction, while the possibility of enhancing its poor aqueous solubility with CDs was probed by means of equilibriu...

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Bibliographic Details
Main Authors: Mino R. Caira, Susan A. Bourne, Halima Samsodien, Vincent J. Smith
Format: Article
Language:English
Published: Beilstein-Institut 2015-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
complexation
cyclodextrin
2-methoxyestradiol
solubility
X-ray diffraction
Online Access:https://doi.org/10.3762/bjoc.11.281

Internet

https://doi.org/10.3762/bjoc.11.281

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