<i>APOBEC3B</i> Gene Expression in Ductal Carcinoma In Situ and Synchronous Invasive Breast Cancer

<i>APOBEC3B</i> Gene Expression in Ductal Carcinoma In Situ and Synchronous Invasive Breast Cancer

The underlying mechanism of the progression of ductal carcinoma in situ (DCIS), a non-obligate precursor of invasive breast cancer (IBC), has yet to be elucidated. In IBC, Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) is upregulated in a substantial proportion of cas...

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Bibliographic Details
Main Authors: Anieta M. Sieuwerts, Shusma C. Doebar, Vanja de Weerd, Esther I. Verhoef, Corine M. Beauford, Marie C. Agahozo, John W.M. Martens, Carolien H.M. van Deurzen
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
APOBEC3B
gene expression
breast cancer
ductal carcinoma in situ
infiltrating breast cancer
PIK3CA
Online Access:https://www.mdpi.com/2072-6694/11/8/1062

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