Elucidating the Underlying Functional Mechanisms of Breast Cancer Susceptibility Through Post-GWAS Analyses

by Mahdi Rivandi, Mahdi Rivandi, John W. M. Martens, John W. M. Martens, Antoinette Hollestelle
Published 2018-08-01

Pan-cancer landscape of homologous recombination deficiency

by Luan Nguyen, John W. M. Martens, Arne Van Hoeck, Edwin Cuppen
Published 2020-11-01

Association between acquired uniparental disomy and homozygous mutations and HER2/ER/PR status in breast cancer.

by Musaffe Tuna, Marcel Smid, Dakai Zhu, John W M Martens, Christopher I Amos
Published 2010-11-01

Mitochondrial RNA Expression and Single Nucleotide Variants in Association with Clinical Parameters in Primary Breast Cancers

by Marjolein J. A. Weerts, Marcel Smid, John A. Foekens, Stefan Sleijfer, John W. M. Martens
Published 2018-12-01

A Systematic Review of the Use of Circulating Cell-Free DNA Dynamics to Monitor Response to Treatment in Metastatic Breast Cancer Patients

by Elisabeth M. Jongbloed, Teoman Deger, Stefan Sleijfer, John W. M. Martens, Agnes Jager, Saskia M. Wilting
Published 2021-04-01

ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen

by Anieta M. Sieuwerts, Márcia A. Inda, Marcel Smid, Henk van Ooijen, Anja van de Stolpe, John W. M. Martens, Wim F. J. Verhaegh
Published 2020-03-01

Increased MAPK1/3 Phosphorylation in Luminal Breast Cancer Related with PIK3CA Hotspot Mutations and Prognosis

by Diana Ramirez-Ardila, A. Mieke Timmermans, Jean A. Helmijr, John W.M. Martens, Els M.J.J. Berns, Maurice P.H.M. Jansen
Published 2017-10-01

Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression

by Jiang Ren, Marcel Smid, Josephine Iaria, Daniela C. F. Salvatori, Hans van Dam, Hong Jian Zhu, John W. M. Martens, Peter ten Dijke
Published 2019-09-01

Estrogens and Progestogens in Triple Negative Breast Cancer: Do They Harm?

by Mark van Barele, Bernadette A. M. Heemskerk-Gerritsen, Yvonne V. Louwers, Mijntje B. Vastbinder, John W. M. Martens, Maartje J. Hooning, Agnes Jager
Published 2021-05-01

Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention

by Esmee Koedoot, Eline van Steijn, Marjolein Vermeer, Román González-Prieto, Alfred C. O. Vertegaal, John W. M. Martens, Sylvia E. Le Dévédec, Bob van de Water
Published 2021-03-01

Defining the dimensions of circulating tumor cells in a large series of breast, prostate, colon, and bladder cancer patients

by Pauline A. J. Mendelaar, Jaco Kraan, Mai Van, Leonie L. Zeune, Leon W. M. M. Terstappen, Esther Oomen‐de Hoop, John W. M. Martens, Stefan Sleijfer
Published 2021-01-01

<i>APOBEC3B</i> Gene Expression in Ductal Carcinoma In Situ and Synchronous Invasive Breast Cancer

by Anieta M. Sieuwerts, Shusma C. Doebar, Vanja de Weerd, Esther I. Verhoef, Corine M. Beauford, Marie C. Agahozo, John W.M. Martens, Carolien H.M. van Deurzen
Published 2019-07-01

The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer.

by Jingjing Liu, Anieta M Sieuwerts, Maxime P Look, Michelle van der Vlugt-Daane, Marion E Meijer-van Gelder, John A Foekens, Antoinette Hollestelle, John W M Martens
Published 2016-01-01

5-Fluorouracil treatment induces characteristic T>G mutations in human cancer

by Sharon Christensen, Bastiaan Van der Roest, Nicolle Besselink, Roel Janssen, Sander Boymans, John W. M. Martens, Marie-Laure Yaspo, Peter Priestley, Ewart Kuijk, Edwin Cuppen, Arne Van Hoeck
Published 2019-10-01

High ctDNA molecule numbers relate with poor outcome in advanced ER+, HER2− postmenopausal breast cancer patients treated with everolimus and exemestane

by Dinja T. Kruger, Maurice P.H.M. Jansen, Inge R.H.M. Konings, Wouter M. Dercksen, Agnes Jager, Jamal Oulad Hadj, Stefan Sleijfer, John W.M. Martens, Epie Boven
Published 2020-03-01

ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen

by Anieta M. Sieuwerts, M\u00e1rcia A. Inda, Marcel Smid, Henk van Ooijen, Anja van de Stolpe, John W. M. Martens, Wim F. J. Verhaegh
Published 2020-03-01

Global proteomic characterization of microdissected estrogen receptor positive breast tumors

by Tommaso De Marchi, Ning Qing Liu, Christoph Sting, Marcel Smid, Mila Tjoa, René B.H. Braakman, Theo M. Luider, John A. Foekens, John W.M. Martens, Arzu Umar
Published 2015-12-01

A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy

by Ronan P. McLaughlin, Jichao He, Vera E. van der Noord, Jevin Redel, John A. Foekens, John W. M. Martens, Marcel Smid, Yinghui Zhang, Bob van de Water
Published 2019-07-01

Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy

by Esmee Koedoot, Liesanne Wolters, Marcel Smid, Peter Stoilov, Gerhard A. Burger, Bram Herpers, Kuan Yan, Leo S. Price, John W. M. Martens, Sylvia E. Le Dévédec, Bob van de Water
Published 2021-03-01

A Method to Correlate mRNA Expression Datasets Obtained from Fresh Frozen and Formalin-Fixed, Paraffin-Embedded Tissue Samples: A Matter of Thresholds.

by Dana A M Mustafa, Anieta M Sieuwerts, Marcel Smid, Vania de Weerd, Marcel van der Weiden, Marion E Meijer-van Gelder, John W M Martens, John A Foekens, Johan M Kros
Published 2015-01-01