BAGE Hypomethylation Is an Early Event in Colon Transformation and Is Frequent in Histologically Advanced Adenomas

BAGE Hypomethylation Is an Early Event in Colon Transformation and Is Frequent in Histologically Advanced Adenomas

We showed earlier that BAGE (B melanoma antigen) loci are hypermethylated in normal tissues and hypomethylated in 98% of human cancers. More recently, we provided evidence that hypomethylation of BAGE loci represents an informative marker for colon cancer detection. In this study, we show that hypom...

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Bibliographic Details
Main Authors: Alla Rynditch, Frédéric Bibeau, Vasily V. Gordiyuk, Andriy P. Lutsyk, Sylvain Kirzin, Janick Selves, Isabelle Rivals, Marie-Elisabeth Brun, Erica Lana, Albertina De Sario
Format: Article
Language:English
Published: MDPI AG 2009-11-01
Series:Cancers
Subjects:
BAGE
DNA hypomethylation
adenomas
colorectal cancer
biomarker
COBRA
Online Access:http://www.mdpi.com/2072-6694/1/1/3/

Internet

http://www.mdpi.com/2072-6694/1/1/3/

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