Previous exposure to dengue virus is associated with increased Zika virus burden at the maternal-fetal interface in rhesus macaques.

Previous exposure to dengue virus is associated with increased Zika virus burden at the maternal-fetal interface in rhesus macaques.

Concerns have arisen that pre-existing immunity to dengue virus (DENV) could enhance Zika virus (ZIKV) disease, due to the homology between ZIKV and DENV and the observation of antibody-dependent enhancement (ADE) among DENV serotypes. To date, no study has examined the impact of pre-existing DENV i...

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Bibliographic Details
Main Authors: Chelsea M Crooks, Andrea M Weiler, Sierra L Rybarczyk, Mason I Bliss, Anna S Jaeger, Megan E Murphy, Heather A Simmons, Andres Mejia, Michael K Fritsch, Jennifer M Hayes, Jens C Eickhoff, Ann M Mitzey, Elaina Razo, Katarina M Braun, Elizabeth A Brown, Keisuke Yamamoto, Phoenix M Shepherd, Amber Possell, Kara Weaver, Kathleen M Antony, Terry K Morgan, Christina M Newman, Dawn M Dudley, Nancy Schultz-Darken, Eric Peterson, Leah C Katzelnick, Angel Balmaseda, Eva Harris, David H O'Connor, Emma L Mohr, Thaddeus G Golos, Thomas C Friedrich, Matthew T Aliota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009641

Internet

https://doi.org/10.1371/journal.pntd.0009641

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