Prognostic implication of molecular subtypes and response to neoadjuvant chemotherapy in 760 gastric carcinomas: role of Epstein–Barr virus infection and high‐ and low‐microsatellite instability

Prognostic implication of molecular subtypes and response to neoadjuvant chemotherapy in 760 gastric carcinomas: role of Epstein–Barr virus infection and high‐ and low‐microsatellite instability

Abstract Epstein–Barr virus positivity (EBV(+)) and high‐microsatellite instability (MSI‐H) have been identified as molecular subgroups in gastric carcinoma. The aim of our study was to determine the prognostic and predictive relevance of these subgroups in the context of platinum/5‐fluorouracil (5‐...

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Bibliographic Details
Main Authors: Meike Kohlruss, Bianca Grosser, Marie Krenauer, Julia Slotta‐Huspenina, Moritz Jesinghaus, Susanne Blank, Alexander Novotny, Magdalena Reiche, Thomas Schmidt, Liridona Ismani, Alexander Hapfelmeier, Daniel Mathias, Petra Meyer, Matthias M Gaida, Lukas Bauer, Katja Ott, Wilko Weichert, Gisela Keller
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:The Journal of Pathology: Clinical Research
Subjects:
microsatellite instability
Epstein–Barr virus
adenocarcinoma
gastric
gastro‐oesophageal junction
outcome
Online Access:https://doi.org/10.1002/cjp2.137

Internet

https://doi.org/10.1002/cjp2.137

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