A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasisResearch in context

A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasisResearch in context

Background: Miltefosine has been used successfully to treat visceral leishmaniasis (VL) in India, but it was unsuccessful for VL in a clinical trial in Brazil. Methods: To identify molecular markers that predict VL treatment failure whole genome sequencing of 26 L. infantum isolates, from cured and...

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Main Authors: Juliana B.T. Carnielli, Kathryn Crouch, Sarah Forrester, Vladimir Costa Silva, Sílvio F.G. Carvalho, Jeziel D. Damasceno, Elaine Brown, Nicholas J. Dickens, Dorcas L. Costa, Carlos H.N. Costa, Reynaldo Dietze, Daniel C. Jeffares, Jeremy C. Mottram
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418303876

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http://www.sciencedirect.com/science/article/pii/S2352396418303876

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