Lung and liver transplantation in patients with alpha-1 antitrypsin deficiency

Alpha-1 antitrypsin (AAT) augmentation is effective in slowing the progression of emphysema due to AAT deficiency (AATD) but cannot prevent eventual progression to end-stage lung disease and complete respiratory failure, which is the leading cause of death for individuals with severe AATD. When pati...

Full description

Bibliographic Details
Main Authors: Martin R. Zamora, Ali Ataya
Format: Article
Language:English
Published: SAGE Publishing 2021-06-01
Series:Therapeutic Advances in Chronic Disease
Online Access:https://doi.org/10.1177/20406223211002988