PLK2 modulation of enriched TAp73 affects osteogenic differentiation and prognosis in human osteosarcoma

PLK2 modulation of enriched TAp73 affects osteogenic differentiation and prognosis in human osteosarcoma

Abstract There are three subtypes of undifferentiated human conventional osteosarcoma (HCOS): osteoblastic osteosarcoma (OOS), chondroblastic osteosarcoma (COS), and fibroblastic osteosarcoma (FOS). HCOS also exhibits heterogeneous pathological maldifferentiation in individual patients. Currently, t...

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Bibliographic Details
Main Authors: Wenhu Li, Xianliao Zhang, Xinhua Xi, Yufa Li, Hong Quan, Shifeng Liu, Liqi Wu, Penghuan Wu, Wenxing Lan, Yongjun Shao, Haomiao Li, Kebing Chen, Zhengbo Hu
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Cancer Medicine
Subjects:
osteogenic differentiation
Osteosarcoma
PDX
PLK2
TAp73
Online Access:https://doi.org/10.1002/cam4.3066

Internet

https://doi.org/10.1002/cam4.3066

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