Semen IgM, IgG1, and IgG3 Differentially Associate With Pro-Inflammatory Cytokines in HIV-Infected Men

Semen IgM, IgG1, and IgG3 Differentially Associate With Pro-Inflammatory Cytokines in HIV-Infected Men

Genital inflammation significantly increases the risk for HIV infection. The seminal environment is enriched in pro-inflammatory cytokines and chemokines. Here, we investigated the interplay between semen cytokines and humoral immunity to understand whether the characteristics of semen antibodies ar...

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Bibliographic Details
Main Authors: Thevani Pillay, Parveen Sobia, Abraham Jacobus Olivier, Kapil Narain, Lenine J. P. Liebenberg, Sinaye Ngcapu, Mesuli Mhlongo, Jo-Ann S. Passmore, Cheryl Baxter, Derseree Archary
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
semen
HIV
HIV-specific antibodies
immunoglobulins
cytokines
genital inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03141/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.03141/full

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