Potential Role of Dipeptidyl Peptidase IV in the Pathophysiology of Heart Failure

Potential Role of Dipeptidyl Peptidase IV in the Pathophysiology of Heart Failure

Dipeptidyl peptidase IV (DPPIV) is a widely expressed multifunctional serine peptidase that exists as a membrane-anchored cell surface protein or in a soluble form in the plasma and other body fluids. Numerous substrates are cleaved at the penultimate amino acid by DPPIV, including glucagon-like pe...

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Bibliographic Details
Main Authors: Thiago A. Salles, Leonardo dos Santos, Valério G. Barauna, Adriana C. C. Girardi
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:International Journal of Molecular Sciences
Subjects:
glucagon-like peptide-1
brain natriuretic peptide
stromal cell-derived factor-1
renal function
cardiac dysfunction
natriuresis
cardioprotection
renoprotection
Online Access:http://www.mdpi.com/1422-0067/16/2/4226

Internet

http://www.mdpi.com/1422-0067/16/2/4226

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