Use of bacterially expressed dsRNA to downregulate Entamoeba histolytica gene expression.

BACKGROUND:Modern RNA interference (RNAi) methodologies using small interfering RNA (siRNA) oligonucleotide duplexes or episomally synthesized hairpin RNA are valuable tools for the analysis of gene function in the protozoan parasite Entamoeba histolytica. However, these approaches still require tim...

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Bibliographic Details
Main Authors: Carlos F Solis, Julien Santi-Rocca, Doranda Perdomo, Christian Weber, Nancy Guillén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2793006?pdf=render