An original Eurasian haplotype, HLA-DRB1*14:54-DQB1*05:03, influences the susceptibility to idiopathic achalasia.

An original Eurasian haplotype, HLA-DRB1*14:54-DQB1*05:03, influences the susceptibility to idiopathic achalasia.

Idiopathic achalasia is a relatively infrequent esophageal motor disorder for which major histocompatibility complex (MHC) genes are well-identified risk factors. However, no information about HLA-achalasia susceptibility in Mexicans has previously been reported. We studied a group of 91 patients di...

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Bibliographic Details
Main Authors: Janette Furuzawa-Carballeda, Joaquín Zuñiga, Diana I Hernández-Zaragoza, Rodrigo Barquera, Eduardo Marques-García, Luis Jiménez-Alvarez, Alfredo Cruz-Lagunas, Gustavo Ramírez, Nora E Regino, Ramón Espinosa-Soto, Edmond J Yunis, Fernanda Romero-Hernández, Daniel Azamar-Llamas, Enrique Coss-Adame, Miguel A Valdovinos, Samuel Torres-Landa, Axel Palacios-Ramírez, Blanca Breña, Edgar Alejandro-Medrano, Axel Hernández-Ávila, Julio Granados, Gonzalo Torres-Villalobos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6084941?pdf=render

Internet

http://europepmc.org/articles/PMC6084941?pdf=render

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