Effects of Tissue Pressure on Transgene Expression Characteristics via Renal Local Administration Routes from Ureter or Renal Artery in the Rat Kidney

Effects of Tissue Pressure on Transgene Expression Characteristics via Renal Local Administration Routes from Ureter or Renal Artery in the Rat Kidney

We previously developed a renal pressure-mediated transfection method (renal pressure method) as a kidney-specific in vivo gene delivery system. However, additional information on selecting other injection routes and applicable animals remains unclear. In this study, we selected renal arterial and u...

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Bibliographic Details
Main Authors: Natsuko Oyama, Haruyuki Takahashi, Maho Kawaguchi, Hirotaka Miyamoto, Koyo Nishida, Masako Tsurumaru, Mikiro Nakashima, Fumiyoshi Yamashita, Mitsuru Hashida, Shigeru Kawakami
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
naked pdna
physical methods
pressure
gene transfection
kidney
local administration
renal artery
renal ureter
Online Access:https://www.mdpi.com/1999-4923/12/2/114

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https://www.mdpi.com/1999-4923/12/2/114

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