Gelatinases Cleave Dentin Sialoprotein Intracellularly

Dentin sialoprotein (DSP), the NH2-terminal fragment of dentin sialophosphoprotein (DSPP), is essential for dentin formation and further processed into small fragments inside the odontoblasts. Gelatinases, including matrix metalloproteinases 9 (MMP9) and MMP2, were able to cleave DSP(P) in tooth str...

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Bibliographic Details
Main Authors: Xiaohui Gou, Yifan Xue, Huiwen Zheng, Guobin Yang, Shuo Chen, Zhi Chen, Guohua Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00686/full