Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease

Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease

Abstract Background Chronic obstructive pulmonary disease (COPD) is currently the third leading cause of death and there is a huge unmet clinical need to identify disease biomarkers in peripheral blood. Compared to gene level differential expression approaches to identify gene signatures, network an...

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Bibliographic Details
Main Authors: Ma’en Obeidat, Yunlong Nie, Virginia Chen, Casey P. Shannon, Anand Kumar Andiappan, Bernett Lee, Olaf Rotzschke, Peter J. Castaldi, Craig P. Hersh, Nick Fishbane, Raymond T. Ng, Bruce McManus, Bruce E. Miller, Stephen Rennard, Peter D. Paré, Don D. Sin
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Respiratory Research
Subjects:
COPD
FEV1
Blood
mRNA
Gene expression
Co-expression
Online Access:http://link.springer.com/article/10.1186/s12931-017-0558-1

Internet

http://link.springer.com/article/10.1186/s12931-017-0558-1

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