Molecular basis of differential B-pentamer stability of Shiga toxins 1 and 2.

Molecular basis of differential B-pentamer stability of Shiga toxins 1 and 2.

Escherichia coli strain O157:H7 is a major cause of food poisoning that can result in severe diarrhea and, in some cases, renal failure. The pathogenesis of E. coli O157:H7 is in large part due to the production of Shiga toxin (Stx), an AB(5) toxin that consists of a ribosomal RNA-cleaving A-subunit...

Full description

Bibliographic Details
Main Authors: Deborah G Conrady, Michael J Flagler, David R Friedmann, Bradley D Vander Wielen, Rhett A Kovall, Alison A Weiss, Andrew B Herr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3010993?pdf=render

Internet

http://europepmc.org/articles/PMC3010993?pdf=render

Similar Items