Prenatal exposure to dexamethasone in the mouse alters cardiac growth patterns and increases pulse pressure in aged male offspring.

Exposure to synthetic glucocorticoids during development can result in later cardiovascular and renal disease in sheep and rats. Although prenatal glucocorticoid exposure is associated with impaired renal development, less is known about effects on the developing heart. This study aimed to examine t...

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Bibliographic Details
Main Authors: Lee O'Sullivan, James S M Cuffe, Tamara M Paravicini, Sally Campbell, Hayley Dickinson, Reetu R Singh, Oksan Gezmish, M Jane Black, Karen M Moritz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3723833?pdf=render