Generation of monoclonal antibodies against highly conserved antigens.

Generation of monoclonal antibodies against highly conserved antigens.

BACKGROUND: Therapeutic antibody development is one of the fastest growing areas of the pharmaceutical industry. Generating high-quality monoclonal antibodies against a given therapeutic target is very crucial for the success of the drug development. However, due to immune tolerance, some proteins t...

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Bibliographic Details
Main Authors: Hongzhe Zhou, Yunbo Wang, Wei Wang, Junying Jia, Yuan Li, Qiyu Wang, Yanfang Wu, Jie Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2699554?pdf=render

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http://europepmc.org/articles/PMC2699554?pdf=render

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