Is it all that bad when living with an intracellular protozoan? The role of Trypanosoma cruzi calreticulin in angiogenesis and tumor growth

The immune system protects against disease, but may aberrantly silence immunity against altered self, with consequent development of malignancies. Among the components of the endoplasmic reticulum (ER), important in immunity, is calreticulin (CRT) that, in spite of its residence in the ER, can be tr...

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Bibliographic Details
Main Authors: GALIA eRAMIREZ-TOLOZA, LORENA eAGUILAR-GUZMAN, CAROLINA eVALCK, PAULA eABELLO, LUIS ARTURO FERREIRA
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Oncology
Subjects:
c1q
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00382/full