YM155 inhibits retinal pigment epithelium cell survival through EGFR/MAPK signaling pathway

AIM: To investigate YM155's effect on retinal pigment epithelium (RPE) cells' viability and the potential regulatory mechanisms. METHODS: Human immortalized RPE cell lines (ARPE-19 cell line) were processed with YM155 and epidermal growth factor (EGF). ARPE-19 cell viability was detected b...

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Bibliographic Details
Main Authors: Teng Li, Hong-Bing Zhang, Jia-Min Meng, Bo Yuan, Wen-Juan Lin, Yue Feng, Xiao-Dong Chen
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-04-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://ies.ijo.cn/en_publish/2021/4/20210402.pdf