Joint inflammation related citrullination of functional arginines in extracellular proteins

Joint inflammation related citrullination of functional arginines in extracellular proteins

Abstract We report the extent, specific sites and structural requirements of joint inflammation related citrullination in extracellular proteins. A total of 40 synovial fluid samples derived from chronically inflamed human joints were analysed by heparin-agarose fractionation and LC-MS/MS. Citrullin...

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Bibliographic Details
Main Authors: Kalle H. Sipilä, Vipin Ranga, Pekka Rappu, Markku Mali, Laura Pirilä, Ilona Heino, Johanna Jokinen, Jarmo Käpylä, Mark S. Johnson, Jyrki Heino
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08597-4

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https://doi.org/10.1038/s41598-017-08597-4

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