Metabolic reprogramming of Kaposi's sarcoma associated herpes virus infected B-cells in hypoxia.

Metabolic reprogramming of Kaposi's sarcoma associated herpes virus infected B-cells in hypoxia.

Kaposi's sarcoma associated herpesvirus (KSHV) infection stabilizes hypoxia inducible factors (HIFs). The interaction between KSHV encoded factors and HIFs plays a critical role in KSHV latency, reactivation and associated disease phenotypes. Besides modulation of large-scale signaling, KSHV in...

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Bibliographic Details
Main Authors: Rajnish Kumar Singh, Fengchao Lang, Yonggang Pei, Hem Chandra Jha, Erle S Robertson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5963815?pdf=render

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http://europepmc.org/articles/PMC5963815?pdf=render

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