HLA Allele Associations and V-Beta T-Lymphocyte Expansions in Patients With Psoriasis, Harboring Toxin-Producing Staphylococcus aureus

HLA alleles have been associated with psoriasis. Toxin-producing strains of Staphylococcus aureus behave as superantigens, and if present in patients, might play a role in the exacerbation of psoriatic lesions by activating certain V-beta (Vβ) T-lymphocyte subsets. Allele frequencies in 22 patients...

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Bibliographic Details
Main Authors: Rola Ajib, Lori Janbazian, Elias Rahal, Ghassan M. Matar, Shukrallah Zaynoun, Abdul-Ghani Kibbi, Alexander M. Abdelnoor
Format: Article
Language:English
Published: Hindawi Limited 2005-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/JBB.2005.310