Quercetin suppresses DNA double-strand break repair and enhances the radiosensitivity of human ovarian cancer cells via p53-dependent endoplasmic reticulum stress pathway

Quercetin suppresses DNA double-strand break repair and enhances the radiosensitivity of human ovarian cancer cells via p53-dependent endoplasmic reticulum stress pathway

Cheng Gong,1 Zongyuan Yang,1 Lingyun Zhang,2 Yuehua Wang,2 Wei Gong,2 Yi Liu3 1Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 2Department of Oncology, XiangYang Central Hospital, Hubei University of Arts and Sc...

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Bibliographic Details
Main Authors: Gong C, Yang Z, Zhang L, Wang Y, Gong W, Liu Y
Format: Article
Language:English
Published: Dove Medical Press 2017-12-01
Series:OncoTargets and Therapy
Subjects:
quercetin
p53
endoplasmic reticulum (ER) stress
DNA double-strand breaks
eIF-2α (eukaryotic initiation factor 2α)
ATM kinase;
Online Access:https://www.dovepress.com/quercetin-suppresses-dna-double-strand-break-repair-and-enhances-the-r-peer-reviewed-article-OTT

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https://www.dovepress.com/quercetin-suppresses-dna-double-strand-break-repair-and-enhances-the-r-peer-reviewed-article-OTT

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