CXCL12/CXCR4-Axis Dysfunctions: Markers of the Rare Immunodeficiency Disorder WHIM Syndrome
The WHIM syndrome features susceptibility to human Papillomavirus infection-induced warts and carcinomas, hypogammaglobulinemia, recurrent bacterial infections, B and T-cell lymphopenia, and neutropenia associated with retention of senescent neutrophils in the bone marrow (i.e. myelokathexis). This...
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Format: | Article |
Language: | English |
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Hindawi Limited
2010-01-01
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Series: | Disease Markers |
Online Access: | http://dx.doi.org/10.3233/DMA-2010-0736 |