Inhibition of selenoprotein synthesis by Zika virus may contribute to congenital Zika syndrome and microcephaly by mimicking SELENOP knockout and the genetic disease PCCA

Inhibition of selenoprotein synthesis by Zika virus may contribute to congenital Zika syndrome and microcephaly by mimicking SELENOP knockout and the genetic disease PCCA

Selenium status plays a major role in health impacts of various RNA viruses. We previously reported potential antisense interactions between viral mRNAs and host mRNAs encoding isoforms of the antioxidant selenoprotein thioredoxin reductase (TXNRD). Here, we examine possible targeting of selenoprote...

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Bibliographic Details
Main Authors: Gabrielle P. Dailey, Lakmini S. Premadasa, Jan A. Ruzicka, Ethan Will Taylor
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:BBA Advances
Subjects:
Antisense
Congenital Zika syndrome
Microcephaly
mRNA
Selenium
Selenoprotein P
Online Access:http://www.sciencedirect.com/science/article/pii/S2667160321000223

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http://www.sciencedirect.com/science/article/pii/S2667160321000223

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