Quantification of tapentadol in rat plasma by HPLC with photo diode array detection: Development and validation of a new methodology
Objective: The aim of the present study was to develop and validate a simple HPLC–PDA based method to quantify TAP in rat plasma. Several parameters both in the extraction and detection method were evaluated. The applicability of the method was determined by administering TAP orally to six albino Wi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2017-06-01
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| Series: | Future Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2314724516300140 |